US Patent Application 18365040. HIGH-THROUGHPUT PRECISION GENOME EDITING simplified abstract
Contents
HIGH-THROUGHPUT PRECISION GENOME EDITING
Organization Name
The Board of Trustees of the Leland Stanford Junior University
Inventor(s)
Zachery Smith of Sarasota FL (US)
Hunter Fraser of Stanford CA (US)
HIGH-THROUGHPUT PRECISION GENOME EDITING - A simplified explanation of the abstract
This abstract first appeared for US patent application 18365040 titled 'HIGH-THROUGHPUT PRECISION GENOME EDITING
Simplified Explanation
- The patent application describes a new invention related to high-efficiency genome editing. - The invention includes retron-guide RNA cassettes and vectors containing these cassettes. - Host cells can be transformed with these vectors. - The invention also includes retron donor DNA-guide molecules. - Methods for genome editing and screening of genetic loci are provided. - The invention can be used for the prevention or treatment of genetic diseases. - Kits for genome editing and screening are also provided.
Original Abstract Submitted
The invention provides compositions and methods for high-efficiency genome editing. In some aspects, the invention provides retron-guide RNA cassettes and vectors comprising the cassettes. Also provided are host cells that have been transformed with the vectors. In other aspects, the invention provides retron donor DNA-guide molecules. In some other aspects, methods for genome editing and the screening of genetic loci are provided. In further aspects, methods and compositions are provided for the prevention or treatment of genetic diseases. Kits for genome editing and screening are also provided.
