US Patent Application 18302630. METHOD OF CREATING HUMAN PLURIPOTENT STEM CELL DERIVED BRAIN PERICYTE-LIKE CELLS simplified abstract
METHOD OF CREATING HUMAN PLURIPOTENT STEM CELL DERIVED BRAIN PERICYTE-LIKE CELLS
Organization Name
Wisconsin Alumni Research Foundation
Inventor(s)
Eric V. Shusta of Madison WI (US)
Sean P. Palecek of Verona WI (US)
Matthew Stebbins of Madison WI (US)
METHOD OF CREATING HUMAN PLURIPOTENT STEM CELL DERIVED BRAIN PERICYTE-LIKE CELLS - A simplified explanation of the abstract
This abstract first appeared for US patent application 18302630 titled 'METHOD OF CREATING HUMAN PLURIPOTENT STEM CELL DERIVED BRAIN PERICYTE-LIKE CELLS
Simplified Explanation
- The patent application describes a population of brain pericyte-like cells that are derived from human pluripotent stem cells (hPSCs). - These cells express markers typically found in pericytes, which are cells that play a role in maintaining the blood-brain barrier and regulating blood flow in the brain. - However, these pericyte-like cells do not express a specific marker called ACTA2. - The invention provides a method for generating these pericyte-like cells from hPSCs, which could have potential applications in studying brain development and diseases, as well as in drug discovery and regenerative medicine.
Original Abstract Submitted
A population of brain pericyte-like cells, wherein the cells express pericyte markers but do not express ACTA2 and wherein the cells are generated from hPSCs, is disclosed herein.
