US Patent Application 18248934. GPCR SCREENING METHOD TO IDENTIFY NON-HALLUCINOGENIC COMPOUNDS simplified abstract

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GPCR SCREENING METHOD TO IDENTIFY NON-HALLUCINOGENIC COMPOUNDS

Organization Name

The Regents of the University of California

Inventor(s)

Chunyang Dong of Oakland CA (US)

Calvin Ly of Oakland CA (US)

David Olson of Oakland CA (US)

Lin Tian of Oakland CA (US)

GPCR SCREENING METHOD TO IDENTIFY NON-HALLUCINOGENIC COMPOUNDS - A simplified explanation of the abstract

This abstract first appeared for US patent application 18248934 titled 'GPCR SCREENING METHOD TO IDENTIFY NON-HALLUCINOGENIC COMPOUNDS

Simplified Explanation

The abstract of the patent application describes the invention of new fluorescent biosensors that can be used in various methods related to detecting and measuring the effects of hallucinogenic and antidepressant compounds. The abstract also mentions the availability of suitable kits for these purposes.

  • New fluorescent biosensors have been developed for detecting ligand-induced hallucinogenic conformational changes in G Protein-Coupled Receptors (GPCRs).
  • The biosensors can also be used to detect hallucinogenic compounds and non-hallucinogenic antidepressant compounds.
  • The invention provides a method for measuring the hallucinogenic potential of a compound, as well as the antipsychotic potential of a compound.
  • Suitable kits are available for performing these detection and measurement methods.


Original Abstract Submitted

New fluorescent biosensors are provided for use in methods of detecting a ligand-induced hallucinogenic conformational change of a G Protein-Coupled Receptor (GPCR), detecting a hallucinogenic compound, detecting a non-hallucinogenic antidepressant compound, measuring the hallucinogenic potential of a compound, measuring the antipsychotic potential of a compound, and suitable kits thereof.