US Patent Application 18032710. CELL LYSIS WITH MAGNETIC PARTICLES AND A RESISTOR simplified abstract
Contents
CELL LYSIS WITH MAGNETIC PARTICLES AND A RESISTOR
Organization Name
Hewlett-Packard Development Company, L.P.
Inventor(s)
Alexander Govyadinov of Corvallis OR (US)
Viktor Shkolnikov of Palo Alto CA (US)
CELL LYSIS WITH MAGNETIC PARTICLES AND A RESISTOR - A simplified explanation of the abstract
This abstract first appeared for US patent application 18032710 titled 'CELL LYSIS WITH MAGNETIC PARTICLES AND A RESISTOR
Simplified Explanation
The patent application describes a method for manipulating and lysing cells in a microfluidic channel using magnetic particles and a magnetic field.
- The method involves receiving a biologic sample containing a cell in the microfluidic channel.
- A magnetic field is generated using a magnet, which attracts a group of magnetic particles present in the channel.
- A resistor in the channel is activated to agitate the fluid, causing the magnetic particles to move and lyse the cell.
- This lysis process releases cellular material from the cell, which can be collected and analyzed.
Original Abstract Submitted
A method comprising receiving, at a microfluidic channel, a biologic sample including a cell and providing a magnetic field within the microfluidic channel using a first magnet, wherein the magnetic field attracts a first plurality of magnetic particles disposed within the microfluidic channel. The method further includes activating a first resistor disposed within the microfluidic channel to agitate a volume of fluid within the microfluidic channel, and in response, moving the first plurality of magnetic particles through the microfluidic channel to lyse the cell and to release cellular material from the cell.
