US Patent Application 18029748. PREDICTION OF AN OUTCOME OF A BLADDER OR KIDNEY CANCER SUBJECT simplified abstract

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PREDICTION OF AN OUTCOME OF A BLADDER OR KIDNEY CANCER SUBJECT

Organization Name

KONINKLIJKE PHILIPS N.V.


Inventor(s)

Ralf Dieter Hoffmann of Brueggen (DE)

Monique Stoffels of Eindhoven (NL)

PREDICTION OF AN OUTCOME OF A BLADDER OR KIDNEY CANCER SUBJECT - A simplified explanation of the abstract

This abstract first appeared for US patent application 18029748 titled 'PREDICTION OF AN OUTCOME OF A BLADDER OR KIDNEY CANCER SUBJECT

Simplified Explanation

The patent application describes a method for predicting the outcome of bladder or kidney cancer in a patient. This method involves analyzing the gene expression profiles of specific genes related to immune defense response, T-cell receptor signaling, and PDE4D7 correlation.

  • The method involves determining the gene expression profiles of immune defense response genes, T-cell receptor signaling genes, and PDE4D7 correlated genes in a biological sample from the patient.
  • The prediction of the outcome is based on the analysis of these gene expression profiles.
  • The prediction can be provided to a medical caregiver or the patient themselves.


Original Abstract Submitted

The invention relates to a method of predicting an outcome of a bladder or kidney cancer subject, comprising determining or receiving the result of a determination of a first gene expression profile for each of one or more immune defense response genes, and/or of a second gene expression profile for each of one or more T-Cell receptor signaling genes, and/or of a third gene expression profile for each of one or more PDE4D7 correlated genes, said first, second, and third expression profile(s) being determined in a biological sample obtained from the subject, determining the prediction of outcome based on the first gene expression profile(s), or on the second gene expression profile(s), or on the third gene expression profile(s), or on the first, second, and third gene expression profile(s), and, optionally, providing the prediction to a medical caregiver or the subject.