20250215417. Methods Separa (Ionis Pharmaceuticals, .)
Methods for Separating Certain Oligonucleotide Compounds
Abstract: provided are methods for reducing the amount of a contaminant in a sample containing an oligomeric compound. the method may comprise chromatography using a mobile phase comprising a strong salt and a chaotrope. also provided are oligomeric compounds prepared by the method.
Inventor(s): Stilianos G. Roussis, Claus Andre Frank Rentel
CPC Classification: C12N15/101 ({by chromatography, e.g. electrophoresis, ion-exchange, reverse phase})
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