View source for US Patent Application 18302630. METHOD OF CREATING HUMAN PLURIPOTENT STEM CELL DERIVED BRAIN PERICYTE-LIKE CELLS simplified abstract

=METHOD OF CREATING HUMAN PLURIPOTENT STEM CELL DERIVED BRAIN PERICYTE-LIKE CELLS=


==Organization Name==

[[:Category:Wisconsin Alumni Research Foundation|Wisconsin Alumni Research Foundation]]


[[Category:Wisconsin Alumni Research Foundation]]

==Inventor(s)==

[[:Category:Eric V. Shusta of Madison WI (US)|Eric V. Shusta of Madison WI (US)]][[Category:Eric V. Shusta of Madison WI (US)]]

[[:Category:Sean P. Palecek of Verona WI (US)|Sean P. Palecek of Verona WI (US)]][[Category:Sean P. Palecek of Verona WI (US)]]

[[:Category:Matthew Stebbins of Madison WI (US)|Matthew Stebbins of Madison WI (US)]][[Category:Matthew Stebbins of Madison WI (US)]]

==METHOD OF CREATING HUMAN PLURIPOTENT STEM CELL DERIVED BRAIN PERICYTE-LIKE CELLS - A simplified explanation of the abstract==


This abstract first appeared for US patent application 18302630 titled 'METHOD OF CREATING HUMAN PLURIPOTENT STEM CELL DERIVED BRAIN PERICYTE-LIKE CELLS

==Simplified Explanation==

- The patent application describes a population of brain pericyte-like cells that are derived from human pluripotent stem cells (hPSCs).
- These cells express markers typically found in pericytes, which are cells that play a role in maintaining the blood-brain barrier and regulating blood flow in the brain.
- However, these pericyte-like cells do not express a specific marker called ACTA2.
- The invention provides a method for generating these pericyte-like cells from hPSCs, which could have potential applications in studying brain development and diseases, as well as in drug discovery and regenerative medicine.


==Original Abstract Submitted==

A population of brain pericyte-like cells, wherein the cells express pericyte markers but do not express ACTA2 and wherein the cells are generated from hPSCs, is disclosed herein.



[[Category:C12N5/079]]