View source for 20250188084. Compounds Methods Mod (KRONOS BIO, .)

= COMPOUNDS AND METHODS FOR MODULATING CDK9 ACTIVITY =

'''Abstract''':
provided are heterobifunctional degrader compounds that bind with cyclin dependent kinase 9 (cdk9) and e3 ubiquitin ligase. also provided are methods of treating a subject for a cdk9-mediated disease by administering a therapeutically effective dose of a pharmaceutical composition including the heterobifunctional degrader.

'''Inventor(s)''': [[:Category:WES TROTTER of San Mateo CA US|WES TROTTER]], [[:Category:MARIUS POP of San Mateo CA US|MARIUS POP]], [[:Category:ZHIHUA MA of San Mateo CA US|ZHIHUA MA]], [[:Category:DAVID FREEMAN of San Mateo CA US|DAVID FREEMAN]]

'''CPC Classification''': [[:Category:CPC_C07D487/04|C07D487/04]] (Ortho-condensed systems)


[[Category:Patent Applications]]
[[Category:KRONOS BIO, INC.]]
[[Category:CPC_C07D487/04]]
[[Category:WES TROTTER of San Mateo CA US]]
[[Category:MARIUS POP of San Mateo CA US]]
[[Category:ZHIHUA MA of San Mateo CA US]]
[[Category:DAVID FREEMAN of San Mateo CA US]]

[https://wikipatents.org/index.php?search=20250188084+rejection&title=Special%3ASearch&wprov=acrw1_-1 Search for rejections for patent application number 20250188084]


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