View source for 20250188080. Imidazolonylquinoline Compou (Merck Patent)

= IMIDAZOLONYLQUINOLINE COMPOUNDS AND THERAPEUTIC USES THEREOF =

'''Abstract''':
atropisomers, solid forms, salt forms and deuterated derivatives of the atm inhibitor 8-(1,3-dimethyl-1h-pyrazol-4-yl)-1-(3-fluoro-5-methoxypyridin-4-yl)-7-methoxy-3-methyl-1,3-dihydroimidazo[4,5-c]quinolin-2-one as well as compositions thereof are useful in the inhibition, regulation and/or modulation of signal transduction by atm kinase. the stable atropisomers do not interconvert and are represented by the following formulae:

'''Inventor(s)''': [[:Category:Thomas Fuchss of Bensheim-Auerbach  DE|Thomas Fuchss]], [[:Category:Axel Becker of Seeheim-Jugenheim  DE|Axel Becker]], [[:Category:Holger Kubas of Bad Homburg  DE|Holger Kubas]], [[:Category:Ulrich Graedler of Weinheim  DE|Ulrich Graedler]]

'''CPC Classification''': [[:Category:CPC_C07D471/04|C07D471/04]] (Ortho-condensed systems)


[[Category:Patent Applications]]
[[Category:Merck Patent GmbH]]
[[Category:CPC_C07D471/04]]
[[Category:Thomas Fuchss of Bensheim-Auerbach  DE]]
[[Category:Axel Becker of Seeheim-Jugenheim  DE]]
[[Category:Holger Kubas of Bad Homburg  DE]]
[[Category:Ulrich Graedler of Weinheim  DE]]

[https://wikipatents.org/index.php?search=20250188080+rejection&title=Special%3ASearch&wprov=acrw1_-1 Search for rejections for patent application number 20250188080]


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