US Patent Application 18249865. NUCLEIC ACID-GUIDED NUCLEASES AND USE THEREOF simplified abstract

NUCLEIC ACID-GUIDED NUCLEASES AND USE THEREOF

Organization Name

Massachusetts Institute of Technology

Inventor(s)

Feng Zhang of Cambridge MA (US)

Soumya Kannan of Cambridge MA (US)

Han Altae-tran of Cambridge MA (US)

NUCLEIC ACID-GUIDED NUCLEASES AND USE THEREOF - A simplified explanation of the abstract

This abstract first appeared for US patent application 18249865 titled 'NUCLEIC ACID-GUIDED NUCLEASES AND USE THEREOF

Simplified Explanation

- The patent application is about systems, methods, and compositions for targeting polynucleotides. - The disclosed systems involve non-naturally occurring or engineered DNA or RNA-targeting systems. - These systems include a novel DNA or RNA-targeting nucleic acid-guided nuclease. - The systems also include at least one targeting nucleic acid component, such as a guide RNA. - The invention aims to provide a more efficient and precise method for targeting specific polynucleotides. - The disclosed systems can be used in various applications, such as gene editing or gene therapy. - The patent application emphasizes the non-naturally occurring or engineered nature of the DNA or RNA-targeting systems. - The invention may have potential implications for advancements in genetic research and medical treatments.

Original Abstract Submitted

Systems, methods, and compositions for targeting polynucleotides. More particularly, the disclosure provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting nucleic acid-guided nuclease and at least one targeting nucleic acid component like a guide RNA.