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MOLECULENT AB (20250101503). DETECTION OF PROXIMITY ASSAY PRODUCTS IN SITU

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DETECTION OF PROXIMITY ASSAY PRODUCTS IN SITU

Organization Name

MOLECULENT AB

Inventor(s)

Olof John Ericsson of Solna SE

Fredrik Roos of Solna SE

DETECTION OF PROXIMITY ASSAY PRODUCTS IN SITU

This abstract first appeared for US patent application 20250101503 titled 'DETECTION OF PROXIMITY ASSAY PRODUCTS IN SITU

Original Abstract Submitted

this disclosure provides an in situ proximity assay. in some embodiments, the method may comprise (a) performing a proximity assay on one or more pairs of binding agent—oligonucleotide conjugates that are bound to the sample, in situ, to produce proximity assay reaction products; and (b) labeling the sites in the sample at which the proximity assay reaction products are produced, wherein the labeling comprises hybridizing an oligonucleotide to the proximity assay reaction products and does not involve primer extension.

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