INBIOSE N.V. (20250109419). SIALYLTRANSFERASES FOR THE PRODUCTION OF SIALYLATED OLIGOSACCHARIDES
SIALYLTRANSFERASES FOR THE PRODUCTION OF SIALYLATED OLIGOSACCHARIDES
Organization Name
Inventor(s)
Joeri Beauprez of Zwijnaarde BE
Thomas Decoene of Zwijnaarde BE
Annelies Vercauteren of Zwijnaarde BE
SIALYLTRANSFERASES FOR THE PRODUCTION OF SIALYLATED OLIGOSACCHARIDES
This abstract first appeared for US patent application 20250109419 titled 'SIALYLTRANSFERASES FOR THE PRODUCTION OF SIALYLATED OLIGOSACCHARIDES
Original Abstract Submitted
the present invention is in the technical field of synthetic biology, metabolic engineering and cell cultivation. the present invention relates to newly identified sialyltransferases having alpha-2, 3-sialyltransferase activity on the galactose residue of lactose. the invention also describes methods for the production of a 3′sialylated oligosaccharide using any one of the newly identified sialyltransferases as well as the purification of the 3′sialylated oligosaccharide. the present invention also provides a cell for production of the 3′sialylated oligosaccharide and the use of the cell in a cultivation or incubation.
