George Mason University (20250093360). DNA BASED SENSORS
DNA BASED SENSORS
Organization Name
Inventor(s)
Remi Veneziano of Falls Church VA US
Parag V. Chitnis of Burke VA US
Giovanni Giammanco of Hanover MD US
John R. Cressman of Fairfax VA US
DNA BASED SENSORS
This abstract first appeared for US patent application 20250093360 titled 'DNA BASED SENSORS
Original Abstract Submitted
provided is a nanoparticle comprising: a dna scaffold comprising an attached dye, an attached functional moiety, or a combination thereof. in some embodiments, the dna scaffold comprises a plurality of dna oligonucleotides, wherein each oligonucleotide is independently optionally attached to a dye and/or a functional moiety. provided is a method of cell voltage sensing at a target site comprising providing the nanoparticle of any one of the preceding embodiments at the target site; and monitoring cell voltage at the target site. also provided is a method of fluorescence or absorbance imaging at a target site comprising providing the nanoparticle of any one of the preceding embodiments at the target site; and monitoring fluorescence or absorbance at the target site.