Fred Hutchinson Cancer Center (20250003973). SYNTHETIC CONSTRUCTS AND METHODS FOR PROCESSING ANTIGEN-SPECIFIC CELLS
SYNTHETIC CONSTRUCTS AND METHODS FOR PROCESSING ANTIGEN-SPECIFIC CELLS
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SYNTHETIC CONSTRUCTS AND METHODS FOR PROCESSING ANTIGEN-SPECIFIC CELLS
This abstract first appeared for US patent application 20250003973 titled 'SYNTHETIC CONSTRUCTS AND METHODS FOR PROCESSING ANTIGEN-SPECIFIC CELLS
Original Abstract Submitted
the present disclosure provides methods for detecting antigen-specific cells, such as t cells or b cells, using a proximity ligation assay (pla) in which at least one of the pla probes is a peptide-major histocompatibility (mhc) multimer or a b cell specific antigen bound to an oligonucleotide. also provided are kits for use in such methods.