Deepmind technologies limited (20250069705). MACHINE LEARNING FOR DETERMINING PROTEIN STRUCTURES

MACHINE LEARNING FOR DETERMINING PROTEIN STRUCTURES

Organization Name

deepmind technologies limited

Inventor(s)

Andrew W. Senior of London (GB)

James Kirkpatrick of London (GB)

Laurent Sifre of Paris (FR)

RIchard Andrew Evans of London (GB)

Hugo Penedones of Zurich (CH)

Chongli Qin of London (GB)

Ruoxi Sun of Mountain View CA (US)

Karen Simonyan of London (GB)

John Jumper of London (GB)

MACHINE LEARNING FOR DETERMINING PROTEIN STRUCTURES

This abstract first appeared for US patent application 20250069705 titled 'MACHINE LEARNING FOR DETERMINING PROTEIN STRUCTURES

Original Abstract Submitted

methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for performing protein structure prediction and protein domain segmentation. in one aspect, a method comprises generating a plurality of predicted structures of a protein, wherein generating a predicted structure of the protein comprises: updating initial values of a plurality of structure parameters of the protein, comprising, at each of a plurality of update iterations: determining a gradient of a quality score for the current values of the structure parameters with respect to the current values of the structure parameters; and updating the current values of the structure parameters using the gradient.