Biotechnology patent applications on 7th August 2025
Biotechnology Patent Applications on 7th August 2025
Executive Summary
On 7th August 2025, 152 patent applications related to Biotechnology were published, representing 2.2% of all patent applications for the day. This moderate level of activity shows Biotechnology is gaining significant attention from innovators.
Market Analysis
Leading Organizations
The top organizations driving Biotechnology innovation include:
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- The Broad Institute Inc: 6 applications (3.9% of Biotechnology patents)
- Massachusetts Institute of Technology: 6 applications (3.9% of Biotechnology patents)
- PRESIDENT AND FELLOWS OF HARVARD COLLEGE: 5 applications (3.3% of Biotechnology patents)
- 10x Genomics Inc: 4 applications (2.6% of Biotechnology patents)
- GUARDANT HEALTH INC: 4 applications (2.6% of Biotechnology patents)
These 5 organizations account for 25 applications (16.4% of all Biotechnology patents), indicating a diverse and competitive landscape.
Technology Deep Dive
Core Innovation Areas
Patent applications in Biotechnology encompass several key innovation areas:
- Biotechnology: Core technology area
- Genetic Engineering: Core technology area
- Crispr: Core technology area
- Gene Therapy: Core technology area
Technical Classification Analysis
The most active CPC classifications in Biotechnology include:
- C12N15/86 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media): 22 applications (14.5%)
- C12N15/113 (Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; {Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing (when used in plants): 21 applications (13.8%)
- C12N2310/20 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media): 18 applications (11.8%)
- C12N9/22 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media): 16 applications (10.5%)
- C12N2310/11 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media): 13 applications (8.6%)
- C12N2310/14 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media): 12 applications (7.9%)
- C12N15/85 (for animal cells): 12 applications (7.9%)
- C12N15/11 (DNA or RNA fragments; Modified forms thereof (DNA or RNA not used in recombinant technology,): 12 applications (7.9%)
- C12N2750/14143 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media): 12 applications (7.9%)
- C12N2310/315 (of the backbone): 11 applications (7.2%)
Global Innovation Landscape
Innovation in Biotechnology spans multiple countries:
- US: 403 inventors (64.6%)
- CN: 64 inventors (10.3%)
- JP: 27 inventors (4.3%)
- DE: 21 inventors (3.4%)
- FR: 17 inventors (2.7%)
- SE: 17 inventors (2.7%)
- GB: 9 inventors (1.4%)
- CA: 9 inventors (1.4%)
- CH: 8 inventors (1.3%)
- NL: 7 inventors (1.1%)
The US accounts for 64.6% of inventors in Biotechnology, indicating strong domestic innovation leadership.
Industry Collaborations
Notable collaborations in Biotechnology include:
- The Broad Institute Inc × Massachusetts Institute of Technology: 6 joint applications
- The Broad Institute Inc × PRESIDENT AND FELLOWS OF HARVARD COLLEGE: 4 joint applications
- Massachusetts Institute of Technology × PRESIDENT AND FELLOWS OF HARVARD COLLEGE: 4 joint applications
- Universite D'Aix-Marseille × INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE: 1 joint applications
- Universite D'Aix-Marseille × CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE: 1 joint applications
These collaborations represent 16 joint applications, indicating moderate industry cooperation in Biotechnology.
Leading Inventors
Key inventors driving Biotechnology innovation:
- Feng Zhang of Cambridge MA US: 5 applications
- Yuxiao Wang of Belmont MA US: 2 applications
- Timothy Weeden of Waltham MA US: 2 applications
- John Najim of Waltham MA US: 2 applications
- Romesh R. Subramanian of Framingham MA US: 2 applications
- Mohammed T. Qatanani of Waltham MA US: 2 applications
- Cody A. Desjardins of Waltham MA US: 2 applications
- Brendan Quinn of Waltham MA US: 2 applications
- Zhihong Jane YANG of Menlo Park CA US: 2 applications
- Christian BEIL of Frankfurt am Main DE: 2 applications
Recent Patent Applications
Representative Biotechnology patent applications from 7th August 2025:
20250248376. METHODS AND COMPOSITIONS FOR TREATING NEUROPATHIES CAUSED BY A CNTNAP1 MUTATION
Applicant: Board of Regents The University of Texas System
Abstract: Disclosed herein are methods and compositions useful in treating a neuropathy caused by a CNTNAP1 mutation. Transgenic animal models and cell lines are disclosed for the study of neuropathies caused by a CNTNAP1 mutation. Methods of screening and identifying active agents for the treatment of neuropathies caused by a CNTNAP1 mutation are also provided.
20250248377. NON-HUMAN ANIMALS HAVING A HUMANIZED TSLP GENE, A HUMANIZED TSLP RECEPTOR GENE, AND/OR A HUMANIZED IL7RA GENE
Applicant: Regeneron Pharmaceuticals Inc
Abstract: Disclosed herein are rodents (such as, but not limited to, mice and rats) genetically modified to comprise a humanized Tslp gene, a humanized Tslpr gene, a humanized Il7ra gene, or a combination thereof. Compositions and methods for making such genetically modified rodents, as well as methods of using such genetically modified rodents as an animal model for diseases such as allergic diseases and cancer are provided.
20250248378. TRANSGENIC ANIMALS FOR MERCURY BIOREMEDIATION
Applicant: Macquarie University
Abstract: There is provided a transgenic animal comprising heterologous nucleic acid encoding a bacterial organomercurial lyase and/or a bacterial mercuric reductase, wherein the transgenic animal expresses the bacterial organomercurial lyase and/or a bacterial mercuric reductase to reduce the toxicity of a mercury compound.
20250248379. piRNA-BASED CONSTRUCTS FOR REGULATING GENE EXPRESSION AND METHODS OF USE THEREOF
Applicant: Rutgers The State University of New Jersey
Abstract: This disclosure is based, in part, on the unexpected discovery that a piRNA-based construct is able to silence genes that are essential for transmission and/or infection of pathogens. The disclosed constructs and methods of use thereof capitalize on the role piRNAs play in transcriptional silencing and general immunity and enable development of transgenic approaches to inhibit transmission of human and crop diseases.
20250248406. NOVEL INSECT INHIBITORY PROTEINS
Applicant: Monsanto Technology LLC
Abstract: Pesticidal proteins exhibiting inhibitory, suppressive, and toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4064 and TIC4064 amino acid sequence variants. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequence...
Market Implications
Innovation Intensity
With 152 applications in a single day, Biotechnology demonstrates very high innovation intensity, suggesting rapid technological advancement and strong commercial interest.
Competitive Landscape
Innovation in Biotechnology involves 142 organizations, indicating a highly competitive and diverse landscape with many players investing in R&D.
Technology Outlook
Emerging themes in Biotechnology patents include: methods, nucleic, cells, compositions, that, suggesting future development in these areas.
The current patent activity level suggests Biotechnology is in a growth phase with increasing market adoption and investment.
Related Technology Areas
Innovation in Biotechnology often intersects with other emerging technologies:
- Medical Devices: 491 applications
- Semiconductors: 489 applications
- Cybersecurity: 223 applications
- 5G Technology: 203 applications
- Renewable Energy: 180 applications
- Internet of Things: 160 applications
- Generative AI: 152 applications
- Environmental Tech: 143 applications