Basf se (20240294894). IMPROVED BACILLUS HOST CELL WITH ALTERED REMA/REMB PROTEIN simplified abstract
IMPROVED BACILLUS HOST CELL WITH ALTERED REMA/REMB PROTEIN
Organization Name
Inventor(s)
Max Fabian Felle of Ludwigshafen (DE)
Mathis Appelbaum of Ludwigshafen (DE)
Christopher Sauer of Ludwigshafen (DE)
Stefan Janewein of Ludwigshafen (DE)
IMPROVED BACILLUS HOST CELL WITH ALTERED REMA/REMB PROTEIN - A simplified explanation of the abstract
This abstract first appeared for US patent application 20240294894 titled 'IMPROVED BACILLUS HOST CELL WITH ALTERED REMA/REMB PROTEIN
Simplified Explanation
This patent application is about a genetically modified bacterial host cell that can produce biological compounds more efficiently by cultivating it in a specific way.
Key Features and Innovation
- Genetic modifications in the remA and/or remB gene of the host cell
- Increased production of at least one polypeptide of interest
- Cultivating the bacterial host cell to enhance production efficiency
Potential Applications
The technology can be applied in various industries such as pharmaceuticals, biotechnology, and agriculture for the production of specific biological compounds.
Problems Solved
This technology addresses the problem of low production efficiency of biological compounds in host cells, leading to increased yields and cost-effectiveness.
Benefits
- Enhanced production of biological compounds
- Cost-effective production process
- Increased efficiency in cultivating host cells
Commercial Applications
- Pharmaceutical companies can use this technology to produce therapeutic proteins more efficiently.
- Biotechnology companies can benefit from increased yields of enzymes and other biological compounds.
- Agricultural companies can improve crop yields by utilizing this technology for the production of plant-related compounds.
Prior Art
Readers can explore prior research on genetic modifications in bacterial host cells for increased production of biological compounds to understand the existing knowledge in this field.
Frequently Updated Research
Researchers are continuously studying ways to further optimize the genetic modifications in host cells for even higher production yields and efficiency.
Questions about the Technology
What are the potential drawbacks of using genetically modified host cells for increased production of biological compounds?
Genetically modified organisms may raise concerns about safety, environmental impact, and regulatory approval processes.
How does the cultivation method affect the production of biological compounds in the host cell?
The cultivation method plays a crucial role in providing the necessary conditions for the host cell to efficiently produce the desired biological compounds.
Original Abstract Submitted
the present invention relates to a host cell for increased production of biological compounds. specifically, the invention relates to a host with genetic modifications in the rema and/or remb gene. the present invention further relates to a method for increased production of at least one polypeptide of interest based on cultivating the bacterial host cell of the present invention.