Arrowhead Pharmaceuticals, Inc. (20250092072). Trialkyne Linking Agents and Methods of Use
Trialkyne Linking Agents and Methods of Use
Organization Name
Arrowhead Pharmaceuticals, Inc.
Inventor(s)
Erich Altenhofer of Madison WI US
Jeffrey Carlson of Madison WI US
Matthew Fowler-watters of Madison WI US
Trialkyne Linking Agents and Methods of Use
This abstract first appeared for US patent application 20250092072 titled 'Trialkyne Linking Agents and Methods of Use
Original Abstract Submitted
described are improved linking agents that are useful for facilitating the attachment of targeting groups, pharmacokinetic (pk) enhancers or modifiers, or other delivery agents to oligonucleotides. the described linking agents may exhibit improved reaction yields, stability, and biological activity, particularly when used in connection with oligonucleotide-based compounds, such as rna interference (rnai) agents.
