REGULATORY NUCLEIC ACID SEQUENCES

Organization Name

ASKLEPIOS BIOPHARMACEUTICAL, INC.

Inventor(s)

Jorge Omar Yanez-cuna of Midlothian GB

Juan Manuel Iglesias of Midlothian GB

Sinclair Cooper of Midlothian GB

Michael L. Roberts of Midlothian GB

Antonia Evripioti of Midlothian GB

REGULATORY NUCLEIC ACID SEQUENCES

This abstract first appeared for US patent application 20250129381 titled 'REGULATORY NUCLEIC ACID SEQUENCES

Original Abstract Submitted

the present invention relates to regulatory nucleic acid sequences, in particular muscle-specific promoters, elements thereof, and other such nucleic acid sequences, that are capable of enhancing muscle-specific expression of genes. the invention also relates to expression constructs, vectors and cells comprising such muscle-specific regulatory nucleic acid sequences, and to methods of their use. the regulatory nucleic acid sequences are of particular utility for gene therapy applications, but also find utility in other areas such as bioprocessing and biotechnology.