ABS Global, Inc. (20250129385). GENE-EDITING METHODS FOR EMBRYONIC STEM CELLS
GENE-EDITING METHODS FOR EMBRYONIC STEM CELLS
Organization Name
Inventor(s)
Benjamin Beaton of DeForest WI US
Rebecca Krisher of Cottage Grove WI US
Andrew Mark Cigan of Madison WI US
Michael Mclachlan of Verona WI US
GENE-EDITING METHODS FOR EMBRYONIC STEM CELLS
This abstract first appeared for US patent application 20250129385 titled 'GENE-EDITING METHODS FOR EMBRYONIC STEM CELLS
Original Abstract Submitted
the present disclosure relates generally to methods for improving traits or fitness in cattle, pigs, or aquatic organisms via gene editing. in particular, the methods comprise modifying genes in embryonic stem cells of livestock (e.g., cattle, pigs, or fish) for the purpose of improving a trait (e.g., promoting pathogen resistance, fertility, lactation, and native traits that support more rapid growth or feed efficiency). the methods particularly include crispr-cas9 editing of porcine and bovine embryonic stem cells. also disclosed herein are methods of producing and cultivating porcine embryonic stem cells under feeder free conditions.