ENHANCED FLUORESCENCE SIGNAL THROUGH THE APPLICATION OF AROMATIC ADDITIVES ONTO THE MICROSCOPY SAMPLE FOR STANDARD FLUORESCENCE, FLUORESCENCE MICROSCOPY AND COMBINED FLUORESCENCE MALDI MICROSCOPY/IMAGING

Abstract: methods for enhancing a fluorescence intensity of a sample by adding an aromatic compound thereto. workflows for a combined fluorescence-maldi microscopy/imaging instrument also are disclosed comprising combining maldi imaging and fluorescence imaging of the same sample in one sample preparation step. the presently disclosed workflow reduces the sampling time to one workday and minimizes sample degradation.

Inventor(s): Ethan YANG, Kristine GLUNDE, Caitlin TRESSLER, Scot Charles KUO, Hoku Kahele WEST-FOYLE, Xinyi Elaine SHEN

CPC Classification: G01N33/6851 (involving proteins, peptides or amino acids {(involving lipoproteins )})

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