METHOD FOR PRODUCING REGULATORY T CELLS

Abstract: disclosed are: a method for producing a cell population containing regulatory t cells, the method comprising (1) culturing a cell population containing pluripotent stem cell-derived cd4 t cells in the presence of at least one substance selected from the group consisting of a cdk8 and/or cdk19 inhibitor, a tnfr2 agonist, an mtor inhibitor, and a tgf-�r agonist; a cell population containing regulatory t cells obtained by the method; and a medicine containing the cell population containing regulatory t cells.

Inventor(s): Shin KANEKO, Hisashi YANO, Takayuki SATO, Keiko SEKIYA

CPC Classification: C12N5/0637 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media ))

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