VARIANT ANTIBODIES THAT BIND GAMMA-DELTA T CELL RECEPTORS

Abstract: the present invention relates to antibodies capable of binding a human v�9v�2 t cell receptor. the invention further relates to pharmaceutical compositions comprising the antibodies of the invention and to uses of the antibodies of the invention for medical treatment.

Inventor(s): Paul Willem Henri Ida PARREN, Robertus Cornelis ROOVERS, Johannes Jelle VAN DER VLIET, David LUTJE HULSIK, Peter Alexander Gerardus Maria MACHIELSEN, Michiel VAN WESTERHOVEN, Lisa Anna KING, Felix-Lennart FENNEMANN, Charlotte Merette MOUSSET, Anton Egbert Peter ADANG

CPC Classification: C07K16/2809 (PEPTIDES (peptides in foodstuffs ; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs ; preparations for medicinal purposes ; peptides containing beta-lactam rings ; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, ; ergot alkaloids of the cyclic peptide type ; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids ; macromolecular products derived from proteins ; preparation of glue or gelatine ; single cell proteins, enzymes ; genetic engineering processes for obtaining peptides ; compositions for measuring or testing processes involving enzymes ; investigation or analysis of biological material ))

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