COMPOSITION FOR ENHANCING ACTIVITY OF NATURAL KILLER CELLS

Abstract: the present invention relates to a composition for enhancing the activity of natural killer cells, and provides a composition for enhancing the activity of natural killer cells, the composition containing, as an active ingredient, a peptide having an amino acid sequence of seq id no: 1. the peptide having the amino acid sequence of seq id no: 1 according to the present invention not only increases the cytotoxicity of natural killer cells but also reduces the fratricide increased by tgf-�, and further improves the sensitivity of the natural killer cells to cancer cells. thus, the peptide having the amino acid sequence of seq id no: 1 can be effectively used as an active ingredient for an anticancer drug or an anticancer adjuvant.

Inventor(s): In Pyo Choi, Haiyoung Jung, Hanna Kim, Suk Ran Yoon, Jae Eun Byun

CPC Classification: C07K7/08 (PEPTIDES (peptides in foodstuffs ; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs ; preparations for medicinal purposes ; peptides containing beta-lactam rings ; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, ; ergot alkaloids of the cyclic peptide type ; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids ; macromolecular products derived from proteins ; preparation of glue or gelatine ; single cell proteins, enzymes ; genetic engineering processes for obtaining peptides ; compositions for measuring or testing processes involving enzymes ; investigation or analysis of biological material ))

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