Phosphoinositide 3-Kinase Inhibitors with a Zinc Binding Moiety

Abstract: the instant application relates to deazapurines, thienopyrimidines and furopyrimidines with zinc-binding moiety based derivatives and their use in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. the instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.

Inventor(s): Xiong CAI, Haixiao ZHAI, Chengjung LAI, Changgeng QIAN

CPC Classification: C07D495/04 (HETEROCYCLIC COMPOUNDS (macromolecular compounds ))

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