CELLS HAVING SOLID TUMOR TARGETING BACKBONE AND USE THEREOF

Abstract: provided are methods and compositions for obtaining functionally enhanced derivative effector cells obtained from directed differentiation of genomically engineered ipscs. also provided are derivative cells having stable and functional genome editing that delivers improved or enhanced therapeutic effects. further provided are therapeutic compositions and the use thereof comprising the functionally enhanced derivative effector cells alone, or with antibodies or checkpoint inhibitors in combination therapies.

Inventor(s): Bahram VALAMEHR, Tom Tong LEE, Martin HOSKING, Eigen PERALTA, Chia-Wei CHANG

CPC Classification: A61K40/4202 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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