COMBINED VACCINE AGAINST MYCOBACTERIUM TUBERCULOSIS

Abstract: the present embodiments provide for a () multiple antigen presenting system (maps) immunogenic composition comprising an immunogenic polysaccharide which induces an immune response, where at least one peptide or polypeptide antigen is associated to the immunogenic polysaccharide by complementary affinity molecules. in some embodiments, the immunogenic polysaccharide can be an antigenic capsular polysaccharide of a , type 5 (cp5) or type 8 (cp8), or a combination of type 5 or type 8 capsular polysaccharide from , or alternatively, a different immunogenic capsular or noncapsular polysaccharide, and where the protein or peptide antigens are indirectly linked via an affinity binding pair. the present -maps immunogenic compositions can elicit both humoral and cellular immune responses to the immunogenic polysaccharide and one or multiple antigens at the same time.

Inventor(s): Fan ZHANG, Richard MALLEY, Yingjie LU

CPC Classification: A61K39/04 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

Search for rejections for patent application number 20250228923