GENERATING AND UTILIZING ADULT HEPATOCYTE ORGANOIDS

Abstract: techniques for generating and utilizing adult hepatocyte organoids are described. an example method includes generating an organoid by culturing hepatocytes obtained from an adult donor in a hepatocyte culture medium. the hepatocyte culture medium includes a basal medium and 5 �m of a tgf-� inhibitor.

Inventor(s): Kelly Rose Stevens, Sarah Henley Saxton, Shannon Nicole Mitchell, Inkyung Kang

CPC Classification: A61K35/407 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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