20250228866. Crystalline Form O (Vividion Therapeutics, .)

CRYSTALLINE FORM OF (R)-1-(3-(3-(4-AMINOPYRIMIDIN-2-YL)-5-CHLOROPHENYL)MORPHOLINO)PROP-2-EN-1-ONE

Abstract: the present disclosure relates to a solid crystalline form of (r)-1-(3-(3-(4-aminopyrimidin-2-yl)-5-chlorophenyl)morpholino)prop-2-en-1-one and to methods for preparing such crystalline form. (r)-1-(3-(3-(4-aminopyrimidin-2-yl)-5-chlorophenyl)morpholino)prop-2-en-1-one is a potent keap1 modulator.

Inventor(s): Wei LIN

CPC Classification: A61K31/5377 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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