COMPOUNDS FOR ENHANCING READ THROUGH OF GENES CONTAINING PREMATURE TERMINATION CODONS AND METHODS FOR MAKING AND USING THE SAME

Abstract: disclosed herein are new aromatic compounds, compositions that include one or more aromatic compounds, and methods of synthesizing the same. also disclosed herein are methods of enhancing readthrough of genes containing premature termination codons with one or more compounds or compositions described herein.

Inventor(s): Neil Castle, Martin Smrcina, Sylvain Lebreton, Ingrid Attinost, Anil Nair, Andrea Fiumana, Rachel Parsons, Mathew Calder, Paul Webb, Jared Marklew, Simon Bedford

CPC Classification: A61K31/5377 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

Search for rejections for patent application number 20250228865