METHODS FOR TREATING DISORDERS AMELIORATED BY MUSCARINIC RECEPTOR ACTIVATION

Abstract: provided herein is a method for treating a disorder ameliorated by muscarinic receptor activation in a patient in need thereof, comprising administering to the patient a muscarinic orthosteric agonist, such as xanomeline and/or a salt thereof and an m1 or m4 muscarinic positive allosteric modulator (pam). related pharmaceutical compositions are also provided.

Inventor(s): Steven PAUL, Christian FELDER, James Allen MONN, Michael POPIOLEK, Samantha YOHN

CPC Classification: A61K31/4439 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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