Rolling Sensor Systems for Detecting Analytes and Diagnostic Methods Related Thereto

Abstract: this disclosure relates to sensing the movement of dna rolling motors comprising microparticles or rods on transduction material in the presence of viruses, microbes, or other analytes for diagnostic testing. in certain embodiments, the presence of viral particles, other target microbial biomolecules, or analytes stall the motor by specifically binding to aptamers crosslinking the analytes to the particles, rods, or surface of the transduction material. it is contemplated that microparticles or other rolling motors move along a surface whereby an aptamer targets an analyte, e.g., viral sars-cov-2, and acts to inhibit, reduce, or restrict the speed, acceleration, or area of movement on the surface indicating the presence of the analyte in the sample.

Inventor(s): Selma Piranej, Khalid Salaita, Alisina Bazrafshan

CPC Classification: G01N33/56983 (for microorganisms, e.g. protozoa, bacteria, viruses)

Search for rejections for patent application number 20250216390