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20250215501. Methods (Cancer Research Technology Limited)

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METHODS OF CANCER PROGNOSIS

Abstract: we describe methods for stratifying a subject affected by prostate cancer into one of two prognostic groups. the first prognostic group may be termed an alternative-evotype group and the second prognostic group may be termed a canonical-evotype group. the canonical-evotype group comprises tumours which evolve over the same or different trajectories to a form of the cancer which may be considered to have a standard form. the alternative-evotype group comprises tumours which evolve over the same or different trajectories to a non-standard or alternative form of the cancer. one of the methods comprises: analysing, using dna and/or rna sequencing, a biological sample obtained from the subject with cancer or metastatic disease, identifying genetic aberrations in the biological sample, and classifying the subject in a first or in a second prognostic group based on the presence of the genetic aberrations.

Inventor(s): Dan Woodcock, David Wedge, Colin Cooper

CPC Classification: C12Q1/6886 (for cancer (immunoassay for cancer ))

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