COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES

Abstract: compounds that either produced a higher proportion or greater absolute number of phenotypically identified na�ve, stem cell memory, central memory t cells, adaptive nk cells, and type i nkt cells are identified. compositions and methods for modulating immune cells including t, nk, and nkt cells for adoptive cell therapies with improved efficacy are provided.

Inventor(s): Jonathan ROSEN, Betsy REZNER, Bahram VALAMEHR, Ryan BJORDAHL, Eigen PERALTA

CPC Classification: C12N5/0646 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media ))

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