MOTOR UNIT CHIP, MANUFACTURING METHOD THEREOF AND METHOD OF DETECTING PATHOLOGICAL EVENT USING THE SAME

Abstract: the present disclosure provides a motor unit chip, a method for manufacturing the motor unit chip, and a method for detecting pathological event using the motor unit chip. the motor unit chip comprises a first hydrogel having parallel micro grooves on a surface; a muscle cell disposed in the parallel micro grooves; a second hydrogel disposed on the first hydrogel and covering the muscle cell; and a motor neuron plated on top of the second hydrogel. with the motor unit in a 3d structure, the motor unit chip of the present application makes detecting pathological event easier.

Inventor(s): Shian-Ying Sung, Yu-Lung Lin, Che-Chang Chang, Ming-Heng Wu, Yi-Fan Chen, Li-Na Wei

CPC Classification: C12M23/16 ({Microfluidic devices; Capillary tubes (integrated microfluidic structures ; microreactors )})

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