20250215004. Azolo C (GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN STIFTUNG ÖFFENTLICHEN RECHTS, UNIVERSITÄTSMEDIZIN)
AZOLO COMPOUNDS FOR TREATMENT OF FIBROTIC DISEASES
Abstract: the present invention relates to an azolo compound of formula (i) for use in the treatment of fibrosis, wherein the azolo compounds normalizes collagen i mrna-levels of tgfb-activated fibroblasts and reverses collagen production to the normal levels that are seen in fibroblasts that are not stimulated.
Inventor(s): Lutz Friedjan TIETZE, Edgar VOSS, Shyam Sundar MOTHUKU, Michael ZEISBERG, Gerd HASENFUSS, Gunsmaa NYAMSUREN
CPC Classification: C07D487/04 (Ortho-condensed systems)
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Categories:
- Patent Applications
- GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN STIFTUNG ÖFFENTLICHEN RECHTS, UNIVERSITÄTSMEDIZIN
- CPC C07D487/04
- Lutz Friedjan TIETZE of Goettingen DE
- Edgar VOSS of Staufenberg DE
- Shyam Sundar MOTHUKU of Telangana IN
- Michael ZEISBERG of Goettingen DE
- Gerd HASENFUSS of Goettingen DE
- Gunsmaa NYAMSUREN of Goettingen DE