20250214938. Process Preparing (Merck Sharp & Dohme LLC)
PROCESS FOR PREPARING ((1S,2S)-2-(5-METHYLPYRIDIN-2-YL)CYCLOPROPYL)-METHANOL
Abstract: the present invention relates to an efficient scalable synthesis of compounds such as (1s,2s)-2-(5-methylpyridin-2-yl)cyclopropyl)methanol, which contains a disubstituted cyclopropane with two stereogenic centers and represents a significant challenging synthetic target.
Inventor(s): John Y. L. Chung, Gao Shang, David R. Snead, Lushi Tan, Francois Levesque, Andrew W. Gibson, David R. Lieberman, Chengqian Xiao, Xiaxia Zhao, Zhenbing Zhao, Donglin Li
CPC Classification: C07D213/30 (HETEROCYCLIC COMPOUNDS (macromolecular compounds ))
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Categories:
- Patent Applications
- Merck Sharp & Dohme LLC
- CPC C07D213/30
- John Y. L. Chung of Edison NJ US
- Gao Shang of Doylestown PA US
- David R. Snead of Santee CA US
- Lushi Tan of Edison NJ US
- Francois Levesque of Morris Plains NJ US
- Andrew W. Gibson of Hertfordshire GB
- David R. Lieberman of Greater London GB
- Chengqian Xiao of Shanghai CN
- Xiaxia Zhao of Shanghai CN
- Zhenbing Zhao of Shanghai CN
- Donglin Li of Shanghai CN