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20250213647. Chemokine Receptor (UNIVERSITY OF SOUTH FLORIDA)

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CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE

Abstract: provided are methods of modulating inflammation, modulating cancer cell trafficking, modulating chemokine receptor heteromerization, or modulating activity of a chemokine receptor by administering to a subject in need thereof a therapeutically effective amount of a modulator of an adrenergic receptor and/or an arginine vasopressin receptor. chemokine receptor modulators can also be administered to the subject. additionally, disclosed are compositions comprising a modulator of an adrenergic receptor and/or an arginine vasopressin receptor, and at least one cytokine receptor modulator.

Inventor(s): Matthias MAJETSCHAK

CPC Classification: A61K38/095 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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