20250213599. Formulation Administration (BioNTech SE)
FORMULATION FOR ADMINISTRATION OF RNA
Abstract: the present invention relates to compositions comprising polyplex formulations for delivery of rna to a target organ or a target cell after parenteral administration, in particular after intramuscular administration. more precisely, the present invention relates to formulations for administration of rna such as self-replicating rna, in particular by intramuscular injection. in more detail, the formulations comprise polyplex particles from single stranded rna and a polyalkyleneimine.
Inventor(s): Ugur Sahin, Heinrich Haas, Annette Vogel, Stephanie Erbar, Kerstin Walzer, Anne Schlegel, Sebastian Hörner, Jorge Herrero Moreno, Thorsten Klamp, Sebastian Kreiter, Mustafa Diken, Philipp Heller
CPC Classification: A61K31/70 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))
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- Patent Applications
- BioNTech SE
- CPC A61K31/70
- Ugur Sahin of Mainz DE
- Heinrich Haas of Mainz DE
- Annette Vogel of Mainz DE
- Stephanie Erbar of Mainz DE
- Kerstin Walzer of Mainz DE
- Anne Schlegel of Mainz DE
- Sebastian Hörner of Mainz DE
- Jorge Herrero Moreno of Mainz DE
- Thorsten Klamp of Mainz DE
- Sebastian Kreiter of Mainz DE
- Mustafa Diken of Mainz DE
- Philipp Heller of Mainz DE