SYSTEM AND METHOD OF USING TEMPORAL MEASUREMENTS OF LOCALIZED RADIATION TO ESTIMATE THE MAGNITUDE, LOCATION, AND VOLUME OF RADIOACTIVE MATERIAL IN THE BODY

Abstract: a system and method for the measurement of radiation emitted from the body, for example, is presented. in one example, radiation sensors (e.g., gamma radiation sensors) may be used to measure activity proximate an injection site as a function of time. in some embodiments, one or more rangefinders may be employed to determine a size and/or position of a subject relative to the radiation sensors to better account for varying material densities within the system in estimating, for example, the amount of radioactive material in the tissue proximate the injection site. with an estimated function of radioactive material proximate the injection site as a function of time known, an estimated arterial input function may be determined, allowing for calculation of a correction factor that may be applied by a clinician during nuclear medical imaging. the magnitude, location, and volume of the radioactive source in the body may also be estimated.

Inventor(s): Steven Perrin, Joshua G. Knowland

CPC Classification: A61B6/037 ({Emission tomography})

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