METHOD FOR DETERMINING AMOUNTS OF NAD METABOLITES FROM SAMPLE AND METHODS AND USES RELATED THERETO

Abstract: the present invention relates to the fields of life sciences and medicine. specifically, the invention relates to methods and kits for preparing an extract comprising metabolites such as nad+, nadp+, nadh and nadph from a sample of a subject and to a method for determining amounts of nad+, nadp+, nadh, nadph, nad+/nadh ratio, nadph/nadp+ ratio, nad pool, and/or nadp pool from a sample obtained from a subject. the present invention also relates to an extract comprising metabolites such as nad+, nadp+, nadh and nadph. the methods and kits can be used for diagnostics purposes or for monitoring changes in health status of a person. furthermore, the present invention relates to a method and kit for determining disorders of a subject.

Inventor(s): Liliya EURO, Anu WARTIOVAARA

CPC Classification: C12Q1/32 (involving dehydrogenase)

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