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20250206743. Tyk2 Inh (TAKEDA PHARMACEUTICAL LIMITED)

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TYK2 INHIBITOR SYNTHESIS AND INTERMEDIATES THEREOF

Abstract: described herein are methods of synthesis of a tyrosine-protein kinase 2 (tyk2) inhibitor and to intermediate compounds of the synthesis and methods of making the intermediates. also provided are pharmaceutically acceptable compositions including compounds prepared by the synthetic method and methods of treating disorders using the same.

Inventor(s): Craig E. MASSE, Avinash S. PHADKE, Jon P. LAWSON, Stuart LEVY, Xiaowei YANG, Guisheng WU, Shufeng FAN

CPC Classification: C07D487/04 (Ortho-condensed systems)

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