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20250206734. Bicyclic Heterocycles As Mr (Incyte)

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BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS

Abstract: the present disclosure relates to bicyclic heterocycles of formula (i), and pharmaceutical compositions of the same, that are modulators, antagonists, or inhibitors of the g protein-coupled receptor mrgprx2 and are useful in the treatment of mrgprx2 dependent conditions such as inflammatory diseases.

Inventor(s): Dipendu Das, Kai Liu, Haisheng Wang, Xiaozhao Wang

CPC Classification: C07D471/04 (Ortho-condensed systems)

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