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20250206717. Compound Havin (Innovstone Therapeutics Limited)

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COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF

Abstract: provided is a compound having anti-tumor activity and a use thereof. as a prmt5 inhibitor, the compound has a structure represented by formula (i). experiments have confirmed that these compounds have strong inhibitory effects on prmt5 enzyme activity and tumor cell growth, and can be used as promising compounds for treating prmt5-mediated diseases. furthermore, a specific synthesis method is further studied. the synthesis method is simple in process, convenient to operate, and beneficial to large-scale industrial production and application.

Inventor(s): Yunlong SONG, Wenqing XU, Hongyan KOU, Yongzhao MU, Qun DANG, Pan LI, Zhou YIN, Jianbin MA, Xiaodan FU, Xin CAI, Yan LI

CPC Classification: C07D401/14 (HETEROCYCLIC COMPOUNDS (macromolecular compounds ))

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