20250206708. Oxaziridine Platform Target (Novartis AG)
AN OXAZIRIDINE PLATFORM FOR TARGETING FUNCTIONAL ALLOSTERIC METHIONINE SITES
Abstract: the present disclosure features compounds (e.g., oxaziridine-based compounds), as well as related compositions and methods of use thereof, e.g., for selectively labeling a methionine residue in a target peptide or protein.
Inventor(s): F. Dean Toste, Christopher J. Chang, Audrey Reeves, Angel Gonzalez-valero, Patrick J. Moon, Edward Miller, Richard Alan Lewis, Yipin Lu, Jeffrey M. McKenna
CPC Classification: C07D273/01 (HETEROCYCLIC COMPOUNDS (macromolecular compounds ))
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Categories:
- Patent Applications
- Novartis AG
- CPC C07D273/01
- F. Dean Toste of Berkeley CA US
- Christopher J. Chang of Berkeley CA US
- Audrey Reeves of Berkeley CA US
- Angel Gonzalez-valero of Berkeley CA US
- Patrick J. Moon of Berkeley CA US
- Edward Miller of Berkeley CA US
- Richard Alan Lewis of Baselland CH
- Yipin Lu of Dublin CA US
- Jeffrey M. McKenna of Carlisle MA US