ANTI-alpha-V-beta-8 INTEGRIN ANTIBODIES AND USES THEREOF

Abstract: the present disclosure provides antibodies or antigen-binding fragments thereof that bind specifically to integrin �v�8. the disclosure also provides methods for enhancing an immune response in a subject. the disclosure also provides methods for treating or preventing �v�8-associated disorders. in some embodiments, the antibodies are suitable for use (e.g., therapeutic use) in a human subject.

Inventor(s): Andrew KOLODZIEJ, Eric HAINES, Richard J. MORSE, Tuhina BHATTACHARYA, Paul SLAMAN

CPC Classification: A61K39/39558 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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