TETRACYCLIC COMPOUND AND USE THEREOF

Abstract: the present invention relates to a tetracyclic compound and a use thereof. specifically, the present invention provides a use of a compound of formula i, or an optical isomer, a racemate, a solvate, a pharmaceutically acceptable salt, or a deuterated compound thereof in the preparation of a composition or a formulation for preventing and/or treating tumors. the compound of the present invention has an excellent precise treatment effect on tumors with low or no expression and low or no activity of mitochondrial membrane permeability pores, low or no expression and low or no activity of recombinant peptidylprolyl isomerase f, low or no expression of nnmt gene, high expression of dna methylases, high expression of uhrf 1, a high methylation level at a nucleotide site of the nnmt gene, and/or a high methylation level at a dna cpg site of a nnmt gene region.

Inventor(s): Yufeng SHI, Wenjiang MA, Gang PEI, Peng XIA, Yingcal WANG

CPC Classification: A61K31/4745 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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