SYSTEM AND METHOD FOR CHARACTERIZING BRAIN STATES DURING GENERAL ANESTHESIA AND SEDATION USING PHASE-AMPLITUDE MODULATION

Abstract: a system and method for monitoring and/or controlling a state of consciousness of a subject experiencing anesthesia are provided. in some aspects, the system includes a plurality of sensors placed about the subject and configured to acquire electroencephalogram (“eeg”) data therefrom while the subject is receiving anesthesia, and at least one processor configured to receive the eeg data from the plurality of sensors, and perform a phase-amplitude coupling analysis using the received eeg data to determine a phase-amplitude frequency distribution. the at least one processor is also configured to identify a state of consciousness of the subject using the determined phase-amplitude frequency distribution, and generate a report indicative of the state of consciousness of the subject.

Inventor(s): Patrick L. Purdon, Eran A. Mukamel, Emery N. Brown

CPC Classification: A61B5/4821 ({Determining level or depth of anaesthesia ( takes precedence)})

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