CAPTURING AND AMPLIFYING POLYNUCLEOTIDES USING MOLECULES AND PARTICLES

Abstract: in some examples, a device includes a flowcell including wells, and a plurality of molecules. each molecule may include a single respective polynucleotide. at least some of the wells are coupled to a single respective one of the molecules such that a single respective polynucleotide is coupled to those wells. the device also may include a plurality of particles. each particle may include amplification primers and may be coupled to a single one of the wells via hybridization between an amplification primer of that particle and the polynucleotide of the molecule coupled to that well.

Inventor(s): Xavier von Hatten, Gianluca Artioli, Nam Nguyen, Jonathan Boutell

CPC Classification: C12Q1/6844 (Nucleic acid amplification reactions)

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