ENGINEERED ALPHA-GUAIENE SYNTHASES

Abstract: the current disclosure relates to compositions and methods relating to engineered polypeptides that can encode guaiene synthases that are selective for alpha-guaiene. the engineered polypeptides can also catalyze the production of increased amounts of alpha-guaiene. the disclosure also relates to host cells including the engineered polypeptides that can be used to produce large quantities of alpha-guaiene and its derivatives. the disclosure also relates to methods of producing alpha-guaiene employing said host cells.

Inventor(s): Karolina Kalbarczyk, Amanda Reider Apel

CPC Classification: C12N9/88 (MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media ))

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